AMES, Iowa — Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Metabolic and regulatory networks may be expanded by coupling high-throughput phenotyping and gene expression data with the predictions of a computational model. (Reprinted with permission, Nature, ...

Expect sickle cell disease to be the primary focus of the new Cell and Gene Therapy Access Model, the Centers for Medicare & Medicaid Services said Tuesday. About half of individuals with sickle cell ...

Understanding complex biological pathways, such as gene-gene interactions and gene regulatory networks, is crucial for exploring disease mechanisms and advancing drug development. However, manual ...

Nonprofit founder and CEO, Craig Martin, notes that the industry will likely see more alternative gene therapy ...

Nanoparticle-mediated gene therapy corrects a problem with the placenta that leads to pregnancy issues. The life of billions of people inhabiting Earth is owed to a temporary organ that supported and ...

The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...

Starting in his early teens, Deshawn "DJ" Chow wasn't sure he'd ever be able to live a normal life. Crushing pain episodes brought on by his sickle cell disease were getting progressively worse. "It's ...

A newly published study provides guidance for building accurate mathematical models for gene regulatory networks. Over the last 20 years, researchers in biology and medicine have created Boolean ...