A safe and effective malaria vaccine is high on the wish list of most people concerned with global health. New results suggest how a leading vaccine candidate could be vastly improved. A safe and ...
Plasmodium falciparum resistance to artemisinin derivatives, the first-line antimalarial drug, drives the search for new classes of chemotherapeutic agents. Current discovery is primarily directed ...
A protein that plays a critical role in helping malaria parasites infect red blood cells—known as apical membrane protein 1 (AMA1)—has been found to bind to more than one receptor on the surface of ...
Scientists at La Trobe University have discovered a new antibody-like molecule that could be used in therapy to prevent infection from multiple malaria parasite species. Led by Professor Michael Foley ...
An experimental vaccine designed to spur production of antibodies against a key malaria parasite protein, AMA1, was developed more than decade ago. It showed promise in test-tube and animal ...
Blood-stage malaria vaccines are intended to prevent clinical disease. The malaria vaccine FMP2.1/AS02 A, a recombinant protein based on apical membrane antigen 1 (AMA1) from the 3D7 strain of ...
Writing in Cell Reports, researchers from the National Institute of Allergy and Infectious Diseases (NIAID) and collaborators have presented a multifaceted analysis and structure-function study of a ...
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