Metacaspases and paracaspases are ancestors of caspases. Although both metacaspases and paracaspases possess the caspase-hemoglobinase fold, they exhibit distinct substrate specificity and activation ...
Cytokines of the IL-1 family are central regulators of inflammation and immunity 1. In contrast to most cytokines, several members of the IL-1 family, including IL-1β and IL-18, are synthesized as ...
Caspases are proteases: enzymes that catalyze the breakdown of proteins and are part of the cysteine–aspartic acid protease family. They are vital to the mechanism of programmed cell death in animals ...
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