Eukaryotic translation elongation factors orchestrate the delivery of aminoacyl-tRNAs to the ribosomal A-site during protein synthesis, yet their roles extend far beyond housekeeping. Among these, the ...

A new Northwestern Medicine study published in the Proceedings of the National Academy of Sciences has explored the impacts ...

In a recent article published in Molecular Cell, Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, and Yuki Aoi Ph.D., a postdoctoral ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

Nuclear-encoded regulatory proteins control mitochondrial translation. A few, however, are encoded by the mitochondrial DNA (mtDNA) and are produced by the mitochondrial translation machinery.

Thanks to a first-of-its-kind platform, we are starting to understand how the molecular engine responsible for transcription in mammals controls its speed. A team of researchers from The Rockefeller ...