Celiac disease (CD) is caused by loss of tolerance toward gluten and related cereal products. The delivery of gliadin peptides (GP) to HLA-DR-positive late endosomes (LE) of enterocytes is required ...
Pictures show small intestinal villi from wild type (top) and enterocyte-specific DARS2 knockout mice (bottom) stained for PLIN2 (yellow), TGN38 (red), E-cadherin (green) and DNA (DAPI, blue). The ...
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