By Tarun Sai Lomte Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets for future precision medicine. Somatic genomics ...

Cancer begins when mutations in specific genes override the body’s built-in controls on cell division, allowing rogue cells ...

Schizophrenia is thought to affect 1 in 300 people, or about 0.32 percent of the global population, and treatment options are limited because of a poor understanding of the mechanisms underlying the ...

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

Characteristics of Clonal Hematopoiesis (CH) Mutations - a) We identified somatic mutations in known clonal hematopoiesis of indeterminate potential (CHIP) driver genes using peripheral blood ...

A pivotal study has provided unprecedented insights into the genetic architecture of sweet oranges, highlighting the critical role of somatic mutations in shaping fruit development. By constructing a ...

Accurate genomic profiling is essential for clinical decision-making and optimizing treatment recommendations. Tumor-only sequencing has been adopted by many laboratories to guide precision oncology ...