New genome sequencing algorithm boosts human genome completeness by 20%, improving variant detection and advancing personalized medicine.

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types. The study was led by Ph.D.

Ancient DNA is turning human prehistory into something startlingly intimate. Instead of a clean handoff from one species to another, the last 50,000 years look more like a long, tangled story of ...

Twenty-two years after the completion of the Human Genome Project, scientists have unveiled the most expansive catalog of human genetic variation ever compiled. Across two new papers published ...

Researchers have used a new human reference genome, which includes many duplicated and repeat sequences left out of the original human genome draft, to identify genes that make the human brain ...

Genetic data strengthens the case that humans first settled Sahul around 60,000 years ago, using multiple seafaring routes.

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...