In joint studies, scientists at Heinrich Heine University Düsseldorf (HHU) and University of Tübingen, as well as Gießen University, Freiburg University, Max Planck Institute for Biology Tübingen, US ...

DNA damage is a cellular phenomenon that introduces structural abnormalities in double-stranded DNA. External factors, such as radiation or chemical agents, as well as internal factors, such as ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for improving cancer treatment outcomes. The result was published in Cell Death & ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

DNA ligases are ubiquitous enzymes that catalyse the formation of phosphodiester bonds between adjacent 5′‐phosphate and 3′‐hydroxyl termini in double-stranded DNA. The canonical ligation cycle ...

Bacteria are constantly moving by help of motility organs called flagella or pili to colonize new niches. Also, bacteria can exchange information, like “speaking to each other”, and thus acquire new ...

Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...