We discovered high-titer neutralizing autoantibodies against interleukin-10 in a child with infantile-onset inflammatory bowel disease (IBD), a phenocopy of inborn errors of interleukin-10 signaling.

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death ...

Recent advances in the management of inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, have shown that inhibiting the interaction between the α4β7 integrin and the ...

A team led by scientists at King's College London, in collaboration with national and international partners, has discovered how a specific group of immune cells in the gut—Group 3 Innate Lymphoid ...

In the past, treatment focused on managing symptoms. But this goal has changed, and treatment plans now work toward what’s known as mucosal healing. Your intestinal mucosa, the layer of cells that ...

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from the University of Milan highlights the beneficial effect of inhibiting the death ...

Epirium Bio Presenting New Preclinical Data on its 15-PGDH Inhibitor Program in Inflammatory Bowel Disease at Digestive Disease Week® 2026 15-PGDH inhibition with Epirium's oral small molecules, a ...

AI-based drug developer Insilico Medicine detailed in a peer-reviewed paper how it applied its Chemistry42 platform to develop a treatment for inflammatory bowel disease (IBD) that is in early ...