High-throughput sequencing relies on mechanical and enzymatic techniques to break apart DNA into fragments in a consistent and reliable manner. However, traditional approaches tend to favor DNA ...

In this report, we present OLAF-Seq, a novel strategy to construct a long-read sequencing library such that adjacent fragments are linked with end-terminal duplications. We use the CRISPR-Cas9 nickase ...

AXELIOS 1 delivers a unique combination of accuracy, speed, scalability and cost efficiency, giving laboratories of all sizes the freedom to customise their workflows and explore a wider array of ...

Whole genome sequencing (WGS) is a ubiquitous laboratory technique with applications in drug development, genetic disease diagnosis, and personalized medicine. Researchers who use this valuable tool ...

Genotyping is essential to quantitative and population genetic studies, as well as genomics-assisted breeding in crops and animals. Innovations in DNA sequencing technology over the past decades have ...

This article is based on a poster originally authored by Dagmara Wanda Lewandowska, PhD, Marc Gasser, PhD, Vanina Haunreiter-Dengler, PhD and Eva Meszaros, PhD, which was presented at ELRIG Drug ...

Whole genome analysis plays a critical role in the development of life-saving diagnostics, therapeutics, and vaccines, with growing interest in noncoding regions and Whole genome analysis plays a ...

16S metagenomic sequencing enables targeted exploration of microbial communities by combining amplification of the 16S ribosomal RNA (rRNA) gene, a reliable phylogenetic marker, with next generation ...

New technologies advance scalable library normalization for high-throughput genomics labs and improved amplification accuracy for oncology-focused sequencing workflows where data quality is critical ...