A Q-tip, a tissue and a pizza crust ...

Researchers have found that a new base-editing gene therapy can help treat a rare neurodevelopmental disorder called Snijders Blok–Campeau syndrome caused by mutations in the CHD3 gene. A specialized ...

For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

For the first time, researchers have succeeded in developing an artificial DNA base pair that is based on a different ...

An Ice Age double burial in Italy has yielded a stunning genetic revelation. DNA from a mother and daughter who lived over 12,000 years ago shows that the younger had a rare inherited growth disorder, ...

Umbilical cord blood transplantation has transformed the treatment options for patients with blood cancers and other ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...

Testosterone is often treated as a marker of health and vigor, especially in men. But new genetic evidence suggests it’s not all good: higher lifelong levels of the hormone may also increase the risk ...

This project has been funded with federal funds under Contract No. HHSN263201800029I (75N98021F00009) between the National Academy of Sciences and the Department of Health and Human Services, National ...