A new method reveals hidden rules of gene control

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...

BioVenic Strengthens Its Position in the Rapidly Expanding Veterinary Therapeutics Research Landscape

BioVenic is dedicated to advancing the advancement of veterinary molecular diagnostics through its comprehensive ...

A new method to decode how DNA 'switches' control gene activity

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...
EurekAlert!

Microarray analysis of differential expression of long non-coding RNAs in peripheral blood mononuclear cells in luminal a breast cancer

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers. This study aimed to ...
ascopubs.org

Cross-Comparison Individual Patient-Level Analysis of Three Gene Expression Signatures in Localized Prostate in Over 50,000 Men

Precision Treatment of Patients With GI Cancer Using Pre-emptive DPYD Genotyping/Phenotyping Plus Pharmacokinetic-Guided Dosing of 5-Fluorouracil Primary PCa biopsy samples underwent ...
IEEE

Comprehensive Review of Hybrid Feature Selection Methods for Microarray-Based Cancer Detection

Abstract: Microarray data-based cancer detection advances early diagnosis and personalized medicine by utilizing gene expression data to develop comprehensive cancer profiles, measuring thousands of ...
Scientific Research Publishing

Squassina, A., Manchia, M., Congiu, D., Chillotti, C., Ardau, R. and Del Zompo, M. (2011) The Use of Gene Expression Microarrays and Whole Exome Sequencing in Lithium ...

ABSTRACT: Lithium has long been established as a first-line mood stabilizer in the treatment of bipolar disorder and treatment-resistant depression. In addition to its psychiatric applications, ...
ahajournals.org

Differential Expression Analyses on Human Aortic Tissue Reveal Novel Genes and Pathways Associated With Abdominal Aortic Aneurysm Onset and Progression

Abdominal aortic aneurysms (AAAs) are focal dilatations of the abdominal aorta that expand progressively, increasing their risk of rupture. Rupture of an AAA is associated with high mortality rates, ...
eLife

Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging

The study by Tsai et al. employed multi-omics approaches, including transcriptomic, methylomic, and single-cell RNA-seq, and provided a solid and comprehensive analysis of the correlation between ...